The Vanderbilt Commodores and the Missouri Tigers are set to square off in a SEC battle at 4:15 p.m. ET on Saturday at Memorial Stadium/Faurot Field. Missouri is 3-0 overall and 3-0 at home, while Vanderbilt is 2-1 overall and 0-1 on the road. Missouri is favored by 20.5 points in the latest Missouri vs. Vanderbilt odds via SportsLine consensus, and the over/under is 53.5 points.

Before entering any Missouri vs. Vanderbilt picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks and is off to a 5-2 start on over/under picks this season. Anyone who has followed it has seen strong returns.

The model has simulated Missouri vs. Vanderbilt 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits well over 50% of the time!

So who wins Missouri vs. Vanderbilt, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!